NEUROSTECH

About NEUROSTECH

NEUROSTECH is the world’s only biotechnology company that has designed, patented, tested, and developed human prototypes of fully implantable pumpless devices and smart catheters for the controlled intrathecal delivery of drugs. We harness cerebrospinal fluid (CSF) dynamics to create innovative medical devices that deliver targeted, precise treatment exactly where it is needed. NEUROSTECH’s expertise in bioengineering supports a proprietary pipeline of medical devices, which are approaching clinical trials for neurological conditions. NEUROSTECH provides the safest solutions for novel treatment approaches in neurodegenerative diseases, addressing unmet medical needs for devastating conditions such as Alzheimer’s, Parkinson’s, ALS, and more _________________ TECHNOLOGY Cerebrospinal fluid (CSF) naturally flows through the brain in rhythmic, pulsing waves, creating pressure differentials along the intrathecal space. NEUROSTECH is a global leader in leveraging CSF dynamics to develop innovative medical devices. By harnessing the natural flow of CSF, NEUROSTECH is pioneering the development of groundbreaking medical devices. Our deep understanding of CSF dynamics allows us to design the next generation of intrathecal catheters that power pumpless devices. NEUROSTECH also develops advanced subcutaneous reservoirs with cutting-edge architecture and user-friendly percutaneous ports. Through precise engineering of nanoporous membranes, we achieve full control over selective molecular permeability. _________________ PIPELINE Fully implantable pumpless intrathecal devices enable two key modalities: --> Clearance of toxic molecules from the CNS by intrathecal pseudo-delivery --> Controlled intrathecal drug delivery for optimized distribution of therapies to the CNS Smart catheters for CSF management systems: --> Stand-alone lumbar drainage --> Systems combined with external filter devices for CSF filtration (extracorporeal liquorpheresis)

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